Dust and ice mantles on dust grains play an important role in various processes in protoplanetary disks (PPDs) around a young star, including planetesimal formation, surface chemistry, and being the reservoir of water in habitable zones. In this paper, we perform two-dimensional modeling of rotational disruption of dust grains and ice mantles due to centrifugal force within suprathermally rotating grains spun-up by radiative torques for disks around T-Tauri and Herbig Ae/Be stars. We first study rotational disruption of large composite grains and find that large aggregates could be disrupted into individual nanoparticles via the RAdiative Torque Disruption (RATD) mechanism. We then study rotational desorption of ice mantles and ro-thermal desorption of molecules from the ice mantle. We find that ice mantles in the disk？s warm surface layer and above can be disrupted into small icy fragments, followed by rapid evaporation of molecules. We suggest that the rotational disruption mechanism can replenish the ubiquitous presence of polycyclic aromatic hydrocarbons/nanoparticles in the hot surface layers of PPDs as observed in mid-IR emission, which are presumably destroyed by extreme ultraviolet (UV) stellar photons. We find that the water snowline is more extended in the presence of rotational desorption, which would decrease the number of comets but increase the number of asteroids formed in the solar nebula. Finally, we suggest that RATD breaking up carbonaceous grains more efficiently than it does silicates might resolve the carbon deficit problem measured on the Earth and rocky bodies.